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Structure of the human fetal globin gene locus. |
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| Authors: | P F Little R A Flavell J M Kooter G Annison R Williamson |
| Abstract: | We have derived a 'map' of restriction enzyme sites in and around the human gamma-globin genes. This has enabled us to show that there are two gamma-globin genes per haploid set, that the genes contain 'introns' within the same regions of DNA as the human beta and delta-globin genes, and that the genes are 3,500 base pairs apart. We conclude that the correct gene organisation of the human beta-like globin locus is GgammaAgammadeltabeta. |
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