Subcellular localization of noradrenaline and ATP in C1300 mouse neuroblastoma |
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| Authors: | N. H. Fraeyman W. P. De Potter A. F. De Schaepdryver |
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| Affiliation: | (1) Heymans Institute of Pharmacology, Ghent University Medical School, De Pintelaan 135, B-9000 Ghent, (Belgium) |
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| Abstract: | ![]()
Summary A density and velocity gradient centrifugation study of C1300 mouse neuroblastoma showed that ATP is nearly absent from noradrenaline-containing granules and is mainly localized in mitochondria, suggesting that in this tissue ATP is not involved in the storage of noradrenaline.This work was supported by a grant from the ASLK Cancer Fund (Belgium). |
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