Lipopurealins,novel bromotyrosine derivatives with long chain acyl groups,from the marine spongePsammaplysilla purea |
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| Authors: | H. Wu H. Nakamura J. Kobayashi Y. Ohizumi Y. Hirata |
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| Affiliation: | (1) Mitsubishi-Kasei Institute of Life Sciences, 11 Minamiooya, 194 Machida-shi, Tokyo, Japan;(2) Faculty of Pharmacy, Meijo University, 468 Tempaku, Nagoya, Japan;(3) Present address: Shanghai Institute of Organic Chemistry, Academia Sinica, 345 Linglin Lu, Shanghai, China |
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| Abstract: | ![]()
Summary Lipopurealin-A,-B and-C have been isolated from the Okinawan marine spongePsammaplysilla purea. They are inhibitors of Na, K-ATPase, and the structures have been elucidated on the basis of spectral data. They are bromotyrosine derived structures with saturated long chain acyl parts.Physiologically active marine natural products from Porifera X. Preceding paper: Nakamura, H., Wu, H., Kobayashi, J., Nakamura, Y., Ohizumi, Y., and Hirata, Y., Tetrahedron Lett.26 (1985) 4517. |
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| Keywords: | Marine sponge Psammaplysilla purea enzyme inhibitor Na,K-ATPase purealin lipopurealin |
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