The preparation and application of microbubble contrast agent combining ultrasound imaging and magnetic resonance imaging |
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| Authors: | Fang Yang YiXin Li ZhongPing Chen Ning Gu |
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| Institution: | State Key Laboratory of Bioelectronics, Jiangsu Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China |
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| Abstract: | Encapsulated gas microbubbles are well known as ultrasound contrast agents (UCAs) for medical ultrasound (US) imaging. With the development of shell materials and preparation technologies, the application of microbubbles has been enormously popular in molecular imaging, drug delivery and targeted therapy, etc. The objective of this study is to develop Fe3O4 nanoparticle-inclusion microbubble construct. The in vitro US imaging experiment indicates that the Fe3O4 nanoparticle-inclusion microbubbles have highe... |
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| Keywords: | ultrasound (US) imaging magnetic resonance imaging (MRI) microbubble Fe3O4 nanoparticles double-modality |
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