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Is beta-(4-chlorophenyl)-GABA a specific antagonist of substance P on cerebral cortical neurons? |
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| Authors: | J W Phillis |
| Abstract: | Beta-(4-chlorophenyl)-GABA (Baclofen, Lioresal) antagonized the excitant actions of acetylcholine and substance P to comparable extents. L-glutamate-induced excitation was affected to a lesser extent. These findings do not support the suggestion that beta-(4-chlorophenyl)-GABA is a specific substance P antagonist. |
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