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First episode psychosis with extrapyramidal signs prior to antipsychotic drug treatment |
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| Authors: | William G. Honer Donna J. Lang Lili C. Kopala G. William Macewan Geoffrey N. Smith Eric Y. H. Chen Raymond C. K. Chan |
| Affiliation: | HONER William G 1*,LANG Donna J 2,KOPALA Lili C 1,3,MACEWAN G William 1,SMITH Geoffrey N 1,CHEN Eric Y H 4 & CHAN Raymond C K 5 1 Department of Psychiatry,University of British Columbia,Vancouver,BC,Canada,2 Department of Radiology,3 Department of Psychiatry,Dalhousie University,Halifax,NS,4 Department of Psychiatry,University of Hong Kong,Hong Kong,China,5 Key Laboratory of Mental Health,Institute of Psychology,Chinese... |
| Abstract: | Extrapyramidal movement disorders are common in chronic schizophrenia, and may be an intrinsic feature of the illness as well as related to antipsychotic drug treatment. Similar dysfunctions at illness onset may have implications for outcome, and for under- standing the mechanisms of illness. The objectives were to examine the clinical correlates of pre-treatment movement disorders at first episode of psychosis, and determine associations with neuropsychological function and striatal structure. Never medica... |
| Keywords: | schizophrenia movement disorder basal ganglia antipsychotics cognitive psychosis |
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