|
|||||
|
|
| Thymine and adenine derivatives with pyrene, tetrathiafulvalene and nitronyl nitroxide units： Synthesis and formation of ensembles sensing thymine and adenine molecules | |
| 引用本文： | WANG Zhuo YU Yanxin ZHANG Deqing ZHU Daoben. Thymine and adenine derivatives with pyrene, tetrathiafulvalene and nitronyl nitroxide units： Synthesis and formation of ensembles sensing thymine and adenine molecules[J]. 科学通报(英文版), 2006, 51(16): 1947-1954. DOI: 10.1007/s11434-006-2046-8 |
| 作者姓名： | WANG Zhuo YU Yanxin ZHANG Deqing ZHU Daoben |
| 作者单位： | [1]Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China [2]Department of Chemistry, University of Sciences and Technology of China, Hefei 200026, China [3]Graduate School of Chinese Academy of Sciences, Beijing 100080, China |
| 基金项目： | Acknowledgements This work was supported by the National Natural Science Foundation of China （Grant Nos. 20421101 and 90501003 ）, Chinese Academy of Sciences and the National Science Fund for Distinguished Young Scholars （Grant No. 202225207）. |
| 摘 要： | 1 Introduction It is well known that nucleobases are very important biological molecules. Sensitive and selective probes for nucleotides and nucleobases are highly desirable. A number of modified nucleobases and nucleotides as well as artificial hosts wit… |
| 关 键 词： | 胸腺嘧啶 腺嘌呤 嵌二萘 四硫富瓦烯 硝基氧 合成 |
| 收稿时间： | 2005-12-07 |
| 修稿时间： | 2005-12-072006-03-10 |
Thymine and adenine derivatives with pyrene, tetrathiafulvalene and nitronyl nitroxide units: Synthesis and formation of ensembles sensing thymine and adenine molecules |
|
| Zhuo Wang,Yanxin Yu,Deqing Zhang,Daoben Zhu. Thymine and adenine derivatives with pyrene, tetrathiafulvalene and nitronyl nitroxide units: Synthesis and formation of ensembles sensing thymine and adenine molecules[J]. Chinese science bulletin, 2006, 51(16): 1947-1954. DOI: 10.1007/s11434-006-2046-8 | |
| Authors: | Zhuo Wang Yanxin Yu Deqing Zhang Daoben Zhu |
| Affiliation: | (1) Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100080, China;(2) Department of Chemistry, University of Sciences and Technology of China, Hefei, 200026, China;(3) Graduate School of Chinese Academy of Sciences, Beijing, 100080, China |
| Abstract: | Four thymine (T) and adenine (A) derivatives with pyrene, tetrathiafulvalene and nitronyl nitroxide units (1, 2, 3 and 4) were synthesized and characterized. Fluorescent spectral studies indicate that the corresponding T and A derivatives can form ensembles with the association constant of ca. 104 L/mol. The ensemble of 1 and 2 shows pyrene excimer emission, while that of 1/3 and 2/4 displays rather weak fluorescence due to the “intramolecular” photoinduced electron transfer reactions. Addition of compounds 5 or 6, which is T and A derivatives, respectively, to the ensembles of 1/2, 1/3 and 2/4 results in reduction of excimer emission and enhancement of pyrene fluorescence. These results show that these ensembles are able to sense T and A molecules. |
| Keywords: | nucleobases hydrogen-bonding excimer photoinduced electron transfer fluorescence. |
| 本文献已被 CNKI 维普 万方数据 SpringerLink 等数据库收录！ | |
| 点击此处可从《科学通报(英文版)》浏览原始摘要信息 | |
| 点击此处可从《科学通报(英文版)》下载全文 | |