The entropy characters of point mutation |
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Authors: | GuoJi Ma LiJing Liang YanHui Fan WenJuan Wang JiaQing Dai ZhiFa Yuan |
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Affiliation: | (1) College of Science, Northwest A&F University, Yangling, 712100, China;(2) Bioinformatics Center, Northwest A&F University, Yangling, 712100, China;(3) College of Life Sciences, Northwest A&F University, Yangling, 712100, China |
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Abstract: | The biological diversity, which depends on the genetic material DNA, is the foundation for a species to survive and evolve. The entropy is the best measurement of biological diversity. Based on the sin-gle-parameter and the two-parameter models, here we established some differential equations about the point mutation of a DNA sequence with finite length, as well as some functions describing the processes of the variation in quantities of 4 kinds of bases (A, T, G and C) in the DNA sequence. At the molecular level, we discussed the entropy characteristics of point mutation. The results proved that a species maintained its entropy and evolved in the direction of the increasing biological diversity. In order to testify the theoretical results, we did a series of computer simulations of random point muta- tion in Matlab environment. The results were well consistent with the theoretical researches. |
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Keywords: | point mutation Shannon information entropy biological diversity |
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