脉率变异性估计心率变异性的可行性分析

研究了心率变异性(heart rate variability,HRV)是否可以由脉率变异性(pulse rate variability,PRV)替代,以及HRV与PRV之间的定量关系.同步采集了健康青少年、老年人与心血管病人组各25人的脉搏和心电数据,并通过定量对比分析了HRV与PRV在时域、频域和非线性三个方面的特征参数.结果表明,HRV与PRV二者不是完全一致的,其中健康青少年组的全部参数(SDNN,RMSSD,PNN50,HF,LF,SD_1,SD_2,α_1,α_2,SE,CD和AE;Ratio0.2)均具有一致性,故二者在一定程度上可以互相替代分析;而老年人组和心血管病人组只有部分参数(老年:SDNN,SD_1,SD_2,α_1,α_2,CD,SE和AE;病人:SDNN,SD_2,α_1,α_2,CD和AE;Ratio0.2)具有一致性,其余参数(老年:PNN50,RMSSD,LF和HF;病人:PNN50,RMSSD,LF,HF,SD_1和SE;Ratio≥0.2)都不具有充分的一致性,故二者不可以互相替代分析.

Feasibility Analysis on Pulse Rate Variability as an Estimate of Heart Rate Variability

Whether pulse rate variability (PRV) can be a surrogate of heart rate variability (HRV) was investigated， and their quantitative relationship was also studied. Three groups (healthy adolescents， old people and patients with cardiovascular diseases) were enrolled. Each group has 25 subjects and their pulse waves and ECG data were acquired simultaneously. Furthermore， the differences and relationships between them were analyzed after comparing some characteristic parameters of HRV and PRV in the time domain， frequency domain and nonlinear domain. The results show that HRV and PRV are not exactly the same， but there are some agreements in healthy adolescent group for all the parameters (SDNN， RMSSD， PNN50， HF， LF， SD₁， SD₂， α₁， α₂， SE， CD and AE; Ratio<0.2)， which， in a certain extent， can be replaced. There are insufficient agreements for other parameters (old people: PNN50， RMSSD， LF and HF; Patients: PNN50， RMSSD， LF， HF， SD₁ and SE; Ratio≥0.2) while there are agreements in old people group and patients with cardiovascular disease group for some parameters (old people: SDNN， SD₁， SD₂， SE， α₁， α₂， CD， SE and AE; patients: SDNN， SD₂， α₁， α₂， CD and AE; Ratio<0.2)， so HRV cannot be replaced with PRV.