Increased susceptibility ofTrypanosoma lewisi infected,or decomplemented rats toSalmonella typhimurium |
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| Authors: | K. Nielsen J. Sheppard W. Holmes I. Tizard |
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| Affiliation: | (1) Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, University of Guelph, N1G 2W1 Guelph, Ontario, Canada;(2) Present address: Animal Diseases Research Institute, Health of Animals Branch, Agriculture Canada, Postal Station !["lsquo"]("/content/g6u3541x40038847/xlarge8216.gif") H!["rsquo"]("/content/g6u3541x40038847/xlarge8217.gif") Ottawa, P.O. Box 11300, Ontario, Canada |
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| Abstract: | Summary Rats infected withTrypanosoma lewisi or decomplemented by injection of cobra venom factor or complement activating factor of trypanosomes were found to be more susceptible to infection withSalmonella typhimurium. Decomplemented rats subsequently infected withT. lewisi developed higher blood parasitemia than did normalT. lewisi infected rats.This project is supported by the National Research Council of Canada grant A 0068 and a grant from the International Development Research Center. |
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