| 镉对小鼠体内钙、铁稳态的影响 |
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| 引用本文： | 陈敏,程晓农,谢吉民,高晓钦,荆俊杰.镉对小鼠体内钙、铁稳态的影响[J].江苏大学学报(自然科学版),2000,21(3). |
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| 作者姓名： | 陈敏 程晓农 谢吉民 高晓钦 荆俊杰 |
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| 作者单位： | 1. 镇江医学院无机化学教研室,江苏,镇江,212001
2. 江苏理工大学冶金学院,江苏,镇江,212013 |
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| 基金项目： | 卫生部优秀青年人才科研基金资助项目! ( 96 0 1)，江苏省教委自然科学基金资助项目! ( 970 6 )，镇江医学院博士启动基金资助项目 |
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| 摘 要： | 研究了氯化镉染毒小鼠各组织中镉、钙、铁等金属元素含量及各组织的脏器系数、脂质过氧化物 (LPO)值的变化 ,结果显示染镉后小鼠多数脏器中镉、钙、铁浓度明显高于对照组 ,表明小鼠体内钙、铁的稳定状态受到破坏 ,同时某些组织的脏器系数和LPO含量也明显改变 ,提示脏器内钙、铁等元素含量异常可能是镉引起细胞损伤的重要因素之一
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| 关 键 词： | 镉 中毒 钙 铁 |
Effects of Cadmium on the Steady State of Calcium and Ferrous in Mice Organs |
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| CHEN Min,CHENG Xiao-nong,XIE Ji-min,GAO Xiao-qin,JIN Jun-jie.Effects of Cadmium on the Steady State of Calcium and Ferrous in Mice Organs[J].Journal of Jiangsu University:Natural Science Edition,2000,21(3). |
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| Authors: | CHEN Min CHENG Xiao-nong XIE Ji-min GAO Xiao-qin JIN Jun-jie |
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| Abstract: | The concentrations of Cd, Ca and Fe, the change of weight coefficients and lipid peroxidation(LPO) in the organs of mice exposed by CdCl 2 are studied. The results show that the concentrations of Cd, Ca and Fe in the organs of mice induced by CdCl 2 are significantly higher than those in the control group;the Ca and Fe steady state in mice is disturbed. Meanwhile, the weight coefficients and LPO in some organs are clearly changed. These results suggest that unusual content of Ca and Fe in the organs may be one of the important factors in cell injury caused by cadmium. |
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| Keywords: | cadmium toxicity calcium ferrous |
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