| 基于OCT图像的组织散射系数提取方法及其应用 |
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| 引用本文： | 朱良慧,曾毛毛,赵佳玮,吉雁鸿.基于OCT图像的组织散射系数提取方法及其应用[J].华南师范大学学报(自然科学版),2016,48(4):31-34. |
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| 作者姓名： | 朱良慧 曾毛毛 赵佳玮 吉雁鸿 |
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| 作者单位： | 1.（1.华南师范大学物理与电信工程学院,广州 510006; |
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| 基金项目： | 国家自然科学基金项目(61378089;81571837) |
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| 摘 要： | 采用自制频域光学相干层析（OCT）系统对大鼠的正常和疮伤皮肤进行成像,轴向分辨率为8 m,探测深度3 mm，根据组织对光的吸收特性和OCT成像系统的共聚焦特性，建立了A-scan方向图像灰度随探测深度的单次散射-点扩散函数模型. 利用模型中的散射系数作为量化皮肤疮面诊断的光学评价指标. 测量了正常与疮伤皮肤在各阶段的皮肤衰减系数，证明衰减系数能够定量区分正常与疮伤皮肤.
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| 关 键 词： | 光学相干层析成像 散射系数 皮肤疮面量化 |
| 收稿时间： | 2016-04-14 |
Quantify Wound Skin by Extracting Tissue Scattering Coefficient from OCT Image |
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| ZHU Lianghui;ZENG Maomao;ZHAO Jiawei;JI Yanhong.Quantify Wound Skin by Extracting Tissue Scattering Coefficient from OCT Image[J].Journal of South China Normal University(Natural Science Edition),2016,48(4):31-34. |
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| Authors: | ZHU Lianghui;ZENG Maomao;ZHAO Jiawei;JI Yanhong |
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| Institution: | 1.(1. School of Physics and Telecommunication Engineering,South China Normal University,Guangzhou 510006,China;2.2. Research Center of Biomedical Engineering Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China) |
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| Abstract: | A home-made frequency domain OCT system with axial resolution of 8 m and the detection depth of 3 mm has been built for skin imaging. According to the scattering characteristics of tissue and the confocal nature of OCT system, tissue scattering coefficient was extracted with a confocal scattering model from intensities of A-scan signal. Intensity curve was fitted from single scattering point spread function model to extract scattering coefficient of different syndrome types of skin wound. The skin scattering coefficient of normal skin and wound skin was measured at each stage. The results show that scattering coefficient could be a quantitative evaluation index of skin wound. |
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