| 万古霉素给药的新途径——离子电渗透 |
| |
| 引用本文： | 刘赵昆,王东,丁茹,李刚,刘方.万古霉素给药的新途径——离子电渗透[J].南开大学学报,2007,40(1):105-108. |
| |
| 作者姓名： | 刘赵昆 王东 丁茹 李刚 刘方 |
| |
| 作者单位： | [1]南开大学生命科学学院,天津300071 [2]天津大学精密仪器与光电子工程学院,天津300072 |
| |
| 摘 要： | 离子电渗疗法是一种依靠在身体不同组织间施加电场来增加离子药物渗透率的技术.通过经鼠皮离子电渗水杨酸钠,确定直流电场的促渗效率最高.以万古霉素为渗透药物进行了定量实验,结果显示直流电场对于药物的渗透有明显的促进作用,为新给药途径的临床应用奠定了理论基础.
|
| 关 键 词： | 离子电渗 直流电场 万古霉素 万古霉素 给药途径 离子电渗透 理论 临床应用 作用 显示 结果 定量实验 效率最高 促渗 直流电场 水杨酸钠 鼠皮 渗透率 药物 组织间 依靠 疗法 |
| 文章编号： | 0465-7942(2007)01-0105-04 |
| 修稿时间： | 12 4 2006 12:00AM |
New Way of the Vancomycin Therapy-Iontophoresis |
| |
| Liu Zhaokun,Wang Dong,Ding Ru,Li Gang,Liu Fang.New Way of the Vancomycin Therapy-Iontophoresis[J].Acta Scientiarum Naturalium University Nankaiensis,2007,40(1):105-108. |
| |
| Authors: | Liu Zhaokun Wang Dong Ding Ru Li Gang Liu Fang |
| |
| Institution: | 1. College of Life Sciences, Nankai University, Tianjin 300071, China 2. College of Precision Instrument and Opto- electronics Engineering, Tianjin University, Tianjin 300072, China |
| |
| Abstract: | Iontophoresis is a technique which the permeation rate of ionic drugs into the body is enhanced by applying an electric field between viable tissues. In the present researches, the result showed that DC could be used as the ideal, which meets the need of high efficiency using fresh excised full-thickness skin of mice as in vitro model and sodium salicylate as penetrative drug. DC field can obviously increase the permeation rate of vancomycin. |
| |
| Keywords: | iontophoresis direct current vancomycin |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
