Electro-osmotic and iontophoretic release of noradrenaline from micropipettes |
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Authors: | P. Bevan C. M. Bradshaw R. Y. K. Pun N. T. Slater E. Szabadi |
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Affiliation: | (1) Department of Psychiatry, University of Manchester, Stopford Building, Oxford Road, M13 9PT Manchester, (England);(2) Present address: Preclinical Research, Sandoz AG, CH-4002 Basel, Switzerland |
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Abstract: | Summary The relative contributions of electro-osmosis and iontophoresis to the electrophoretic release of noradrenaline from micropipettes were examined. Electro-osmosis was responsible for 23.1% (±5.0%) of the total rate of release.This work was supported by the Wellcome Trust. We are grateful to Dr M.N. Jones for his help. Some of the results have been communicated to the British Pharmacological Society. Dublin, July 1979. |
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