| 中药双联用复方对养殖鳗鲡主要致病菌的抑制作用研究 |
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| 引用本文： | 李忠琴,关瑞章,郭松林,汪黎虹,刘宏伟.中药双联用复方对养殖鳗鲡主要致病菌的抑制作用研究[J].集美大学学报(自然科学版),2011,16(4):241-245. |
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| 作者姓名： | 李忠琴 关瑞章 郭松林 汪黎虹 刘宏伟 |
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| 作者单位： | 1. 集美大学水产学院,福建厦门361021;教育部鳗鱼产业技术工程研究中心,福建厦门361021
2. 集美大学水产学院,福建厦门361021;教育部鳗鱼产业技术工程研究中心,福建厦门361021;福建省高校水产科学技术与食品安全重点实验室,福建厦门361021 |
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| 基金项目： | 国家公益性行业(农业)科研专项(鳗鱼3-51); 福建省科技计划重点项目(2009N0046); 福建省教育厅重点资助项目(JA09157); 福建省科技厅子课题(2009N2003-1); 厦门市科技局重点项目(3502Z20103023); 集美大学创新团队基金资助项目(2010A003);集美大学博士科研启动基金资助项目(ZQ2008015) |
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| 摘 要： | 筛选单用抑菌作用较强的6种中药药材,依据棋盘法设计15种双联用复方,采用超微药粉琼脂稀释法测定各系列浓度组合的复方对养殖鳗鲡18株常见致病菌的抑制作用.实验结果表明,15种双联用复方对18株致病菌中绝大多数菌株的抑制作用比6种中药单用的抑菌作用强,呈现协同效应(FIC≤1)的比例占85.7%,其中显著协同(FIC≤0....
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| 关 键 词： | 鳗鲡 致病菌 中药双联用 协同抑菌效应 |
Antibacterial Activity Analysis for Double-compounds of Chinese Herbs Against Pathogenic Bacteria from Cultured Eels |
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| LI Zhong-qin,GUAN Rui-zhang,GUO Song-lin,WANG Li-hong,LIU Hong-wei.Antibacterial Activity Analysis for Double-compounds of Chinese Herbs Against Pathogenic Bacteria from Cultured Eels[J].the Editorial Board of Jimei University(Natural Science),2011,16(4):241-245. |
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| Authors: | LI Zhong-qin GUAN Rui-zhang GUO Song-lin WANG Li-hong LIU Hong-wei |
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| Institution: | LI Zhong-qin1,2,GUAN Rui-zhang1,3,GUO Song-lin1,WANG Li-hong1,LIU Hong-wei1,3(1.Fisheries College,Jimei University,Xiamen 361021,China,2.Engineering Research Center ofEel Modern Industrial Technology,Ministry of Education,3.Key Laboratory of Science andTechnology for Aquaculture and Food Safety(Jimei University),Fujian Province,China) |
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| Abstract: | Six Chinese herbs were screened,which had the strong inhibitory effect on pathogenic bacteria from cultured eels in vitro,and were first ground into 5～10 μm powder with ultra-pulverizator.Then they were mixed one by one based on chessboard experimental method to get fifteen kinds of compounds of Chinese herbs.To study antibacterial activity of the double-compounds,minimum inhibitory concentration(MIC) of the double-compounds against eighteen pathogenic bacteria from eels were measured with agar dilution method.The results showed that the fifteen kinds of Chinese herbs double-combinations had synergism antibacterial effects against pathogenic bacteria at different extend,and antibacterial activity of almost all compounds had increased.The ratios of FIC≤1 and FIC≤0.5 to all FIC were 85.7 % and 20.4 % respectively,the proportion of 1
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| Keywords: | eel pathogenic bacteria Chinese herbs combined with double synergistic antibacterial effect |
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