| 苯并(a)芘、三丁基锡及其混合物对褐菖鲉溶菌酶活力的影响 |
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| 引用本文： | 刘睿智,郑榕辉,张纪亮,王重刚.苯并(a)芘、三丁基锡及其混合物对褐菖鲉溶菌酶活力的影响[J].厦门大学学报(自然科学版),2006,45(2):253-256. |
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| 作者姓名： | 刘睿智 郑榕辉 张纪亮 王重刚 |
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| 作者单位： | 厦门大学生命科学学院,福建,厦门,361005 |
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| 基金项目： | 中国科学院资助项目，福建省自然科学基金 |
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| 摘 要： | 以褐菖鲉为材料,每周1次腹腔注射浓度为0.5、1、5、10 mg/kg的苯并(a)芘、三丁基锡及两者的等比例混合物,观察鱼体肾脏、脾脏组织中溶菌酶活力的变化.结果表明,实验浓度的苯并(a)芘、三丁基锡对褐菖鲉肾脏、脾脏中的溶菌酶活力均有一定程度的诱导激活作用,而两者混合暴露56 d后显著抑制溶菌酶活性,表明这两种有机污染物在长时间联合作用下,对褐菖鲉非特异免疫能力会产生不利影响.
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| 关 键 词： | 苯并(a)芘 三丁基锡 溶菌酶 褐菖鲉 |
| 文章编号： | 0438-0479(2006)02-0253-04 |
| 收稿时间： | 05 31 2005 12:00AM |
| 修稿时间： | 2005年5月31日 |
Effect of Benzo(a)pyrene, Tributyltin and Their Mixture on Lysozyme Activities in Sebastiscus marmoratus |
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| LIU Rui-zhi,ZHENG Rong-hui,ZHANG Ji-liang,WANG Chong-gang.Effect of Benzo(a)pyrene, Tributyltin and Their Mixture on Lysozyme Activities in Sebastiscus marmoratus[J].Journal of Xiamen University(Natural Science),2006,45(2):253-256. |
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| Authors: | LIU Rui-zhi ZHENG Rong-hui ZHANG Ji-liang WANG Chong-gang |
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| Institution: | School of Life Sciences, Xiamen University, Xiamen 361005, China |
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| Abstract: | The effects of benzo(a)pyrene(BaP),tributyltin(TBT) and their mixture exposure on lysozyme activity of kidney and spleen in Sebastiscus marmoratus were studied with doses of 0.5,1,5,10 mg/kg of body weight for intraperitoneal injected in experimental condition.The results showed that the lysozyme activities were induced during single exposure,but were inhibited by BaP and TBT cotreatment after 8 weeks.It suggests that combined exposure of the two chemicals for long time will cause detrimental effects on the nonspecific activity in Sebastiscus marmoratus. |
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| Keywords: | benzo(a)pyrene tributyltin lysozyme Sebastiscus marmoratus |
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