A gene required for the specification of dorsal-ventral pattern in Drosophila appears to encode a serine protease |
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Authors: | DeLotto R Spierer P |
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Affiliation: | Département de Biologie moléculaire, Université de Genéve, 30, quai Ernest Ansermet, CH-1211 Geneva, Switzerland. |
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Abstract: | The maternal effect gene snake is required for the establishment of the dorsal-ventral axis during the embryonic development of Drosophila. The molecular cloning of the gene and analysis of a complementary DNA sequence suggest that the gene encodes a serine protease which is structurally similar to proteases involved in blood clotting, peptide processing, and complement fixation pathways. |
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