Irreversible depigmentation of dark mouse hair by T-2 toxin (a metabolite ofFusarium sporotrichioides) and by calcium pantothenate |
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Authors: | R. Schoental A. Z. Joffe B. Yagen |
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Affiliation: | (1) Department of Pathology, The Royal Veterinary College, University of London, NW1 OTU London, (England);(2) Department of Botany and Department of Natural Products, School of Pharmacy, the Hebrew University, Jerusalem, (Israel) |
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Abstract: | Summary T-2 toxin, a trichothecene metabolite of several Fusarium spp. causes depigmentation of dark mouse hair at the site of its application. Calcium pantothenate, though usually considered as antigreying factor, caused depigmentation at the site of its i.p. injections, at high concentration. |
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