Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes |
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| Authors: | L C Timpe T L Schwarz B L Tempel D M Papazian Y N Jan L Y Jan |
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| Institution: | Howard Hughes Medical Institute, University of California, San Francisco 94143. |
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| Abstract: | The Shaker gene of Drosophila melanogaster encodes a potassium-selective ion channel, the 'A' channel, or one of its subunits. A single Shaker messenger RNA species suffices to direct the synthesis of functional A channels in Xenopus oocytes. Physiological characteristics of the A currents induced by two different mRNA species are compared. |
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