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急性颅脑损伤病人血浆脂质过氧化物含量的动态观察
引用本文:马茜,呼志斌.急性颅脑损伤病人血浆脂质过氧化物含量的动态观察[J].西北民族学院学报,1997,18(2):36-38.
作者姓名:马茜  呼志斌
作者单位:兰州医学院第二附属医院神经病研究所,兰州医学院第二附属医院神经病研究所 兰州,730030,兰州,730030
摘    要:报道对49例急性颅脑损伤病人检测伤后不同时间血浆脂质过氧化物含量(LPO)。结果表明损伤组血浆LPO含量显著高于对照组(P<0.001—0.05)。脑损伤后8天内,机体自由基水平明显升高,以伤后第4天最高(P<0.001—0.3)。死亡组血浆LP0含量显著高于生存组(P<0.1)。损伤程度与LPO含量呈密切相关(r=3.5.p<0.001)。提示急性颅脑损伤后颅内膜脂质过氧化反应剧增,血浆LPO含量检测对判断脑损伤程度和评估预后有一定的价值。

关 键 词:颅脑损伤  血浆脂质过氧化物

Continuous Observation of Plasma Lipid Peroxide in Acute Head Injuries
Ma Qian,Hu Zhibing.Continuous Observation of Plasma Lipid Peroxide in Acute Head Injuries[J].Journal of Northwest Minorities University(Natural Science ),1997,18(2):36-38.
Authors:Ma Qian  Hu Zhibing
Institution:Ma Qian,Hu Zhibing,Institute of Neurology,Lanzhou Medical college
Abstract:The plasma concentration of lipid peroxide (LPO) was measured in 49 cases of acute head injuries and 50 cases of healthy control. The results show that the concentration of LPO in injury group was higher than that in control group (p<0.01-0.05). Till 8 days after injuries, LPO was obviously higher than in control group, with the peak at 4th day after injuries (p<0. 01). Plasma LPO concentration was closely corelative with injury degree (r=3.51, p<0.01). It can be conclude that Plasma LPO concentration is useful in the estimation of the degree of head injuries.
Keywords:Head Injuries  Lipid Peroxide
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