Comments on the significance of the quasi-valence number for chemical carcinogenesis |
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| Authors: | R E Lyle Gloria G Lyle |
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| Institution: | (1) Department of Chemistry and Department of Basic Health Sciences, North Texas State University, 76203 Denton, Texas, USA;(2) Texas College of Osteopathic Medicine, 76203 Denton, Texas, USA |
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| Abstract: | Summary A quasi-valence number of less than 3.20 was reported to be significant in correlating carcinogenicity. This criterion has no meaningful relationship since such a large proportion of organic compounds fall in this group, that it provides no selectivity.Acknowledgment. The authors express appreciation to the American Cancer Society (CH-57), the National Institute of Environmental Health Sciences (1-RO1-ES01975-01 PTHB) and the Robert A. Welch Foundation (B-702) for financial assistance of projects related to this paper. |
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