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| 二噻吩并[2,3-b:3',2'-d]噻吩与二噻吩并[3,2-b:2',3'-d]噻吩单醛与双醛的合成 | |
| 引用本文： | 赵东锋,徐莉,王华.二噻吩并[2,3-b:3'''',2''''-d]噻吩与二噻吩并[3,2-b:2'''',3''''-d]噻吩单醛与双醛的合成[J].河南大学学报(自然科学版),2007,37(5):468-473. |
| 作者姓名： | 赵东锋 徐莉 王华 |
| 作者单位： | 1. 河南大学,特种功能材料重点实验室,河南,开封,475004 2. 河南大学,化学化工学院,河南,开封,475004 3. 河南大学,特种功能材料重点实验室,河南,开封,475004;河南大学,化学化工学院,河南,开封,475004 |
| 基金项目： | 国家自然科学基金 , 河南省教育厅科研项目 |
| 摘 要： | 二噻吩并2,3-b:3',2'-d]噻吩单醛与双醛的制备首先通过两种方法产生芳基负离子:1)溴代并三噻吩在四氢呋喃中与正丁基锂发生的溴锂交换;2)用LDA对二噻吩并2,3-b:3',2'-d]噻吩去质子化作用.其后经无水DMF猝灭制备出目标化合物.并利用正丁基锂对二噻吩并3,2-b:2',3'-d]噻吩进行去质子化,从而制备相应的单醛与双醛产物.通过红外、核磁、质谱、高分辨质谱以及元素分析等手段对目标产物进行了表征. |
| 关 键 词： | 醛基化 二噻吩并[2 3-b:3 2'-d]噻吩 二噻吩并[3 2-b:2' 3'-d]噻吩 溴锂交换 去质子化作用 formylation dithieno[2 3-b:3' 2'-d]thiophene dithieno[3 2-b:2' 3'-d]thiophene Br/Li exchange deprotonation 噻吩并 双醛 合成 Formylation HRMS paper used quench reaction mixture generate compounds deprotonation low temperature exchange aromatic thiophene methods 表征 手段 |
| 文章编号： | 1003-4978（2007）05-0468-06 |
| 修稿时间： | 2007-01-08 |
Formylation and Diformylation of Dithieno[2,3-b:3',2'-d]thiophene and Dithieno[3,2-b:2',3'-d]thiophene |
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| ZHAO Dong-feng,XU Li,WANG Hua.Formylation and Diformylation of Dithieno[2,3-b:3'''',2''''-d]thiophene and Dithieno[3,2-b:2'''',3''''-d]thiophene[J].Journal of Henan University(Natural Science),2007,37(5):468-473. | |
| Authors: | ZHAO Dong-feng XU Li WANG Hua |
| Institution: | 1.Key Lab for Special Functional Materials, Henan University, Henan Kai feng 475004, China; 2.College of Chemistry and Chemical Engineering, Henan University, Henan Kai feng 475004, China |
| Abstract: | Formylation and diformylation of dithieno 2,3-b:3',2'-d] thiophene were prepared by two methods. Firstly, aromatic carbanions were prepared by 1) Br/Li exchange of bromo dithieno2,3-b:3',2'-d]thiophene with n-BuLi in THF at low temperature; 2) deprotonation of dithieno2,3-b:3',2'-d]thiophene with LDA. Secondly, dry DMF is used to quench the reaction mixture and generate the title compounds. Aromatic carbanions prepared by n-BuLi for formylation and diformylation of dithieno3,2-b:2',3'-d]thiophene were also reported in this paper. The titled compounds were confirmed by IR, 1H-NMR, 13C-NMR and HRMS. |
| Keywords: | formylation dithieno[2 3-b3' 2'-d]thiophene dithieno[3 2-b2' 3'-d]thiophene Br/Li exchange deprotonation |
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