The effect of ascorbic acid on cadmium accumulation in guinea pig tissues. |
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| Authors: | J Kadrabová A Mad?ric E Ginter |
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| Affiliation: | Institute of Preventive and Clinical Medicine, Bratislava, Czecho-Slovakia. |
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| Abstract: | Accumulation of cadmium in organs of guinea pigs after subchronic oral cadmium treatment (1 mg Cd/animal/24 h) was in the following order: kidneys > liver > heart > testes > brain. The preventive effects of high doses of ascorbic acid (AA) against cadmium deposition were more pronounced in the testes, heart and brain, and in the kidney only after short-term cadmium treatment. Ascorbic acid had no protective effect on cadmium accumulation in the liver. |
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