磁性荧光Fe3O4@APTES-RB复合材料的合成及性能表征

磁性-荧光双功能复合纳米材料同时具有磁性和发光特性,因其在生物医学领域具有潜在的广泛应用,引起了人们的广泛关注.采用3-氨丙基三乙氧基硅烷(APTES)对共沉淀法制备的Fe3O4纳米粒子表面进行修饰,获得氨基化的磁性纳米粒子,然后通过共价法将罗丹明B(RB)结合到其表面,获得分散性和荧光信号均得到改善的磁性/荧光复合纳米粒子.利用荧光光谱仪、透射电子显微镜(TEM)、傅里叶变换红外光谱仪(FTIR)、热重分析仪、X-射线衍射仪(XRD)和振动样品磁强计(VSM)对合成的粒子进行了表征.结果表明,氨基化的Fe3O4纳米粒子和Fe3O4-荧光纳米复合材料粒径基本相同,粒径为6～10 nm;Fe3O4-荧光纳米复合材料的饱和磁化强度为38.1 A.m2/kg,室温下呈现超顺磁性,具有较强的荧光信号.这种新型的磁性荧光纳米复合材料将会在生物医学领域具有广阔的应用前景.

Synthesis and Characterization of Magnetic Fluorescent Fe3 O4@ APTES-RB Nanocomposites

Magnetic-fluorescent nanocomposites show simultaneously magnetic and fluorescent features,which have been attracting great attention,owing to their great potential applications for biological and medical fields.Magnetic Fe3O4 nanoparticles were prepared by coprecipitation,and corresponding aminosilane-modified magnetite nanoparticles were synthesized by surface modification with 3-aminopropyltriethoxysilane(APTES),which were then covalent combination with Rhodamine B(RB) to synthesize Fe3O4-fluorescent nanoparticles.These nanoparticles were studied with fluorospectroscopy,TEM,FTIR,TGA,XRD and VSM.The measurement results showed that both of the aminosilane-modified Fe3O4 nanoparticles and Fe3O4-fluorescent nanoparticles had the diameters of 6~10 nm.The Fe3O4-fluorescent nanocomposites had a saturated magnetization of 38.1 A·m2/kg and showed superparamagnetic properties at room temperature.Nanocomposites showed high fluorescent signal.The new magneto-fluorescent nanoagent has great potential applications for biological and medical fields.