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颞叶癫痫颅内外脑电同步记录的临床研究
引用本文:张光明,周文静,石岩芳,林久銮,王东明,韩宏彦,孙朝晖,左焕琮. 颞叶癫痫颅内外脑电同步记录的临床研究[J]. 科技导报(北京), 2009, 27(17): 84-87
作者姓名:张光明  周文静  石岩芳  林久銮  王东明  韩宏彦  孙朝晖  左焕琮
作者单位:清华大学玉泉医院癫痫中心,北京,100049;中国科学院生物物理研究所,脑与认知科学国家重点实验室,北京,100101;清华大学玉泉医院癫痫中心,北京,100049
基金项目:国家重点基础研究发展计划(973计划)项目,国家自然科学基金项目,清华大学裕元医学科学研究基金项目 
摘    要:探索颅内外脑电图同步记录对颞叶癫痫的临床价值.对难以定侧,高度怀疑为颞叶癫痫,并且诊断为难治性癫痫患者行双颞钻孔,置入颅内电极,同步记录10-20头皮、双侧蝶骨和颅内脑电.对最终确认的颞叶癫痫患者,分析其同步脑电图,测量发作从颅内起源传播到颅内外各个目标电极点的时程,推测发作期放电在颅内外传播顺序.分段记数3 h发作间期双侧蝶骨电极癫痫样放电的数量,分析蝶骨间期放电的定侧意义.颞下、海马、颞极和颞叶中外侧各部位起源的大多数发作在颅内外传播有各自的方式,间期蝶骨电极放电数目病灶侧明显多于非病灶侧.颅内电极对难以定侧的颞叶癫病有关键的帮助,颅内外脑电图同步记录的方法有益于颞叶癫痫灶的定侧.

关 键 词:颞叶癫痫  脑电图  同步记录  定侧

Clinical Study on Synchronous Recording of Intracranial and Extracranial Electroencephalogram in Temporal Lobe Epilepsy
ZHANG Guangming,,ZHOU Wenjing,SHI Yanfang,LIN Jiuluan,WANG Dongming,HAN Hongyan,SUN Zhaohui,ZUO Huancong, .Epileptic Center. Clinical Study on Synchronous Recording of Intracranial and Extracranial Electroencephalogram in Temporal Lobe Epilepsy[J]. Science & Technology Review, 2009, 27(17): 84-87
Authors:ZHANG Guangming    ZHOU Wenjing  SHI Yanfang  LIN Jiuluan  WANG Dongming  HAN Hongyan  SUN Zhaohui  ZUO Huancong   .Epileptic Center
Affiliation:ZHANG Guangming1,2,ZHOU Wenjing1,SHI Yanfang1,LIN Jiuluan1,WANG Dongming1,HAN Hongyan1,SUN Zhaohui1,ZUO Huancong1,2 1.Epileptic Center,Institute of Neurological Disorder,Yuquan Hospital,Tsinghua University,Beijing 100049,China 2.State Key Laboratory of Brain , Cognitive Science,Institute of Biophysics,Chinese Academy Sciences,Beijing 100101,China
Abstract:This paper explores the clinical significance of synchronous recording of intracranial and extracranial EEG in temporal lobe epilepsy.Intracranial electrodes were implanted in highly-suspected refractory temporal lobe epilepsy patients to lateralize the epileptic focus.Intracranial and extracranial EEGs were synchronously recorded and analyzed for finally diagnosed temporal lobe epilepsy patients.Time intervals from seizure onset to every electrode were recorded.The propagation patterns were deduced.Numbers...
Keywords:temporal lobe epilepsy  electroencephalogram  synchronous recording  lateralization  
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