过渡金属酞菁配合物化学修饰电极的研究：Ⅲ.对异烟肼的电催化氧化

研究了异烟肼在过渡金属酞菁配合物化学修饰电极上的电催化氧化行为,发现这些修饰电极对异烟肼的氧化有显著的电催化作用,使其氧化峰电位有所负移,氧化峰电流明显增大,且异烟肼氧化峰电流和其浓度之间有着很好的线性关系,并初步拟定了异烟肼电催化氧化的机理。

STUDIES ON THE TRANSITION METAL PHTHALOCYANINE COORDINATION COMPOUNDS CHEMICALLY MODIFIED ELECTRODES III ELECTROCATALYTIC OXIDATION OF ISONIAZIDE

3, 3', 3', 3'-Tetranitrophthalocyanine coordination compounds of Fe (II), (11) and Cu (11) chemically modified eldctrodes (ML CMEs; M-metal ion , ligand) have been prepared for the first time using chemical adsorption method (glassy trode , 0 = 3mm; ML saturated solution; solvent, N, N -dimethyl formamide). The behaviors of isoniazide at the ML CMEs and the unmodified glassy carbon electrode have gated by the cyclic voltammetry (see the fig. i to fig. 5 and the table ]). The oxkiatior, of was irreversible at the ML CMEs as the unmodified electrode , there was not any cathoclic peak of azide in the studied potential range. Under the same experimental conditions,compared with the unmodified glassy carbon electrode, the anodic peak potential of isoniazide at the ML CMEs shifted negativcty obviously, and the anodic peak current of the isoniazide increased strikingly. So the electrocatalytic fects of the ML CMEs to the oxidation of isoniazide were striking. There was a very good linear relationship between the peak current of the electrocatalytic oxidation and the concentration of isoniaride when the electrodes were the ML CMEs (see the table 3). After scanning one thousand cycles to the Ml. CMEs continuously by trittngular voltage sweep the electrocatalytic activity of NiL CME to the oxiiia tion of isoniazide decreased apparently, but the activities of other ML CMEs changed a little (see the table 2). We preposed that M (11) /M (1) redox sites at the ML CMEs transported electrons from the-adsorbed molecules to the glassy carbon electrode to electrocatalytically oxidate isoniazide.