| 聚乙二醇修饰超氧化物歧化酶某些性质的研究 |
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| 引用本文： | 田芳,韩灵翠.聚乙二醇修饰超氧化物歧化酶某些性质的研究[J].北京理工大学学报,1993,13(4):496-499. |
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| 作者姓名： | 田芳 韩灵翠 |
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| 作者单位： | 北京理工大学化工与材料学院，北京理工大学化工与材料学院，北京理工大学化工与材料学院 北京 100081，北京 100081，北京 100081 |
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| 摘 要： | 用聚乙二醇修饰后,SOD的残留活力为60％～80％,其耐热,耐酸与耐碱效能均高于天然SOD。
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| 关 键 词： | 酶蛋白 聚氧化乙烯 超氧化歧化酶 |
Polyethylene Glycol Modified Superoxide Dismutase and Studies of Its Properties |
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| Tian Fang Han Lingcui Chen Tiansheng.Polyethylene Glycol Modified Superoxide Dismutase and Studies of Its Properties[J].Journal of Beijing Institute of Technology(Natural Science Edition),1993,13(4):496-499. |
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| Authors: | Tian Fang Han Lingcui Chen Tiansheng |
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| Abstract: | The preparation and properties of polyethylene glycol (PEG) modified superoxide dismutase (SOD) are reported. It involves the formation of a reactive intermediate by reacting PEG with succinic anhydride and p-nitrophenol, then coupling of the intermediate with SOD. The remaining activity of PEG-SOD ranged from 60% to 80%, and showed a much higher stability than natural SOD even in higher temperature and acidic or basic surroundings. |
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| Keywords: | enzymic protein modification polyethylene glycols/superoxide dismutase |
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