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Stability of the Sarcin/Ricin domain of 28S RNA in rat ribosome under hydrostatic pressure
Authors:Lü Biao  Li Qing  Liu Wangyi  Ruan Kangcheng
Institution:(1) Shanghai Institute of Biochemistry, Chinese Academy of Sciences, 200031 Shanghai, China
Abstract:Under 2 100 bar of hydrostatic pressure, KNA N-glycosidase can still cleave the N-C bond of adenosine at position 4324 in R/S domain of 28S RNA in rat ribosome, demonstrating that high pressure has no effect on the tertiary structure of S/R domain.
Keywords:hydrostatic pressure  RNA N-glycosidase  S/R domain
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