Urushiol components as mediators in DNA strand scission |
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| Authors: | Ch. Wasser F. Silva E. Rodriguez |
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| Affiliation: | (1) Phytochemistry and Toxicology Laboratory, Department of Developmental & Cell Biology, University of California, 92717 Irvine, California, USA |
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| Abstract: | Summary Poison oak urushiol, a mixture of 3-alk(en)ylcatechol derivatives was found to mediate DNA strand scission in the presence of oxygen and with copper(II) chloride as a catalyst. The reactionis believed to occur via activated reduced oxygen produced during oxidation of the catechol into itso-quinone derivative. |
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| Keywords: | DNA strand scission urushiol poison oak 3-alk(en)ylcatechol |
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