| 不同时期肝硬化大鼠门静脉血与下腔静脉血中内源性硫化氢的比较 |
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| 引用本文： | 张宁,郑勇,李睿,周婷,孙侃,陈卫刚,常向云,杨军.不同时期肝硬化大鼠门静脉血与下腔静脉血中内源性硫化氢的比较[J].石河子大学学报,2009,27(1). |
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| 作者姓名： | 张宁 郑勇 李睿 周婷 孙侃 陈卫刚 常向云 杨军 |
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| 作者单位： | 张宁,ZHANG Ning(石河子大学医学院,新疆石河子,832008);郑勇,李睿,周婷,孙侃,陈卫刚,常向云,杨军,ZHENG Yong,LI Rui,ZHOU Ting,SUN Kan,CHEN Wei-gang,CHANG Xiang-yun,YANG Jun(石河子大学医学院第一附属医院,新疆石河子,832008)
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| 摘 要： | 为观察H2S在不同时期肝硬化大鼠门静脉与下腔静脉血中浓度的变化,探索其在肝硬化发生发展过程中的作用.制备四氯化碳诱导的肝硬化大鼠模型,在第15d、第30d、第52d取大鼠门静脉及下腔静脉血检测H2S浓度.肝硬化早、中、晚期大鼠门静脉血和下腔静脉血中H2S的含量均显著低于正常对照组,且H2S浓度随着肝脏病变的加重而逐渐降低;在肝硬化中期及晚期,门静脉血中H2S的浓度明显低于下腔静脉.结果显示,实验性肝硬化大鼠门静脉血和下腔静脉血中H2S在肝硬化门脉高压高动力循环发生发展中起着重要作用.
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| 关 键 词： | 肝硬化大鼠 门静脉和下腔静脉血 硫化氢浓度 |
A Comparison on the Density of H_2S between the Blood from Portal Vein and the Blood from Inferior Vena Caval of Rats with Hepatic Cirrhosis in Different Stages |
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| ZHANG Ning,ZHENG Yong,LI Rui,ZHOU Ting,SUN Kan,CHEN Wei-gang,CHANG Xiang-yun,YANG Jun.A Comparison on the Density of H_2S between the Blood from Portal Vein and the Blood from Inferior Vena Caval of Rats with Hepatic Cirrhosis in Different Stages[J].Journal of Shihezi University(Natural Science),2009,27(1). |
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| Authors: | ZHANG Ning ZHENG Yong LI Rui ZHOU Ting SUN Kan CHEN Wei-gang CHANG Xiang-yun YANG Jun |
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| Institution: | 1 College of Medicine;Shihezi University;Shihezi;Xingjiang 832008;China;2 The First Afiiliated Hospital of College of Medicine;China |
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| Abstract: | This article aims at observing the changes of H2S density between the blood from portal vein and the blood from inferior vena caval of rats with hepatic cirrhosis in different stages,studies the effect of H2S in the corse in which hyperdynamic circulation in rats with hepatic cirrhosis occurs.H2S density in the blood from portal vein and the blood from inferior vena caval of model rats with hepatic cirrhosis induced with carbone terachloridum is detected respectively on the 15th day,the 30th day and the 52t... |
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| Keywords: | rats with hepatic cirrhosis portal vein and inferior vena caval density of H2S |
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