Inflammatory factors produced by sensitized guinea-pig peripheral blood lymphocytes |
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Authors: | R J Warrington S K Buehler K B Roberts |
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Institution: | (1) Division of Cell Studies, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada |
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Abstract: | Summary The supernatants obtained from stimulated tuberculin-sensitive guinea-pig peripheral blood lymphocytes contain factors that induce a cutaneous inflammatory response in normal guinea-pigs similar to the tuberculin reaction and inhibit the migration of normal guinea-pigs peritoneal exudate cells. There appears to be a correlation between the presence of in vitro migration inhibitory activity and inflammatory activity in vivo. |
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