内分泌扰乱化学物质对斑马鱼生长发育影响研究进展

随着内分泌扰乱化学物质研究的逐渐深入,人们越来越关心其对脊椎动物生长发育的影响。斑马鱼具有胚胎透明、性成熟周期短、繁殖力强等优点,是研究脊椎动物发育生物学的重要模式物种之一,被广泛地应用于内分泌扰乱化学物质的研究。本文综述了内分泌扰乱化学物质对斑马鱼胚胎发育、生长、性别分化、繁殖的影响及其机制,展望了该领域的发展方向。

Advances of studies on Effects of Endocrine Disrupting Chemicals on Growth and Development of Zebrafish (Danio rerio)

There is a growing worldwide concern about the effects of endocrine disrupting chemicals on growth and development of vertebrate. Zebrafish (Danio rerio) is a model vertebrate species in developmental biology researches with characteristics such as transparent embryo, short sexual maturity period and good reproductive performance, and is widely used in researches on effects of endocrine disrupting chemicals. This paper reviews toxic effects of endocrine disrupting chemicals on embryo development, growth, gonadal differentiation and reproduction of zebrafish, discusses the potential mechanisms and future prospects of this field as well.