Australian goats detoxify the goitrogen 3-hydroxy-4(1H) pyridone (DHP) after rumen infusion from an indonesian goat |
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| Authors: | R J Jones J B Lowry |
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| Institution: | (1) CSIRO Division of Tropical Crops and Pastures, Davies Laboratory, P.M.B., Atikenvale, P.O., 4814 Townsville, Queensland, Australia;(2) Research Institute for Animal Production, Bogor, P.O. Box 123, W. Java, (Indonesia) |
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| Abstract: | Summary The failure of Australian goats fedLeucaena leucocephala (leucaena) to degrade 3-hydroxy-4(1H) pyridone (DHP), the goitrogenic metabolite of mimosine, was overcome when they were infused with rumen fluid from an Indonesían goat. The leucaena toxicity problem in Australia may well be solved by transfer of specific bacteria capable of degrading DHP anaerobically.We acknowkledge the assistance of R.G. Megarrity in preparation of the goats in Australia and R. Dixon and staff at the CSIRO Lansdown Research Station for preparation of the feed. In Balai Penelitian Ternak; G. Riding, and Suwandi for the metabolism study facilities, Riad the feeding, Miss Leanne Rochanda sample preparation and Mrs M. Young for veterinary assistance. Analyses were carried out by R. Lowe, Jernih Rosida and Wildan. |
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| Keywords: | Leucaena toxicity goat 3-hydroxy-4(1H) pyridone goitrogenic agent rumen fluid mimosine |
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