| 核仁抗原在白血病诊断中的初步观察 |
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| 引用本文： | 雷思晋,王永潮,王良绪,窦焕福,计惠玲,周渝宽,陈萍生,付又刚,文缓. 核仁抗原在白血病诊断中的初步观察[J]. 北京师范大学学报(自然科学版), 1989, 0(4) |
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| 作者姓名： | 雷思晋 王永潮 王良绪 窦焕福 计惠玲 周渝宽 陈萍生 付又刚 文缓 |
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| 作者单位： | 北京师范大学生物系，北京师范大学生物系，北京医科学大学第三医院，北京医科学大学第三医院，北京医科学大学第三医院，北京医科学大学第三医院，北京医科学大学第三医院，北京医科学大学第三医院，北京医科学大学第三医院 |
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| 摘 要： | 用抗核仁抗原NAg-1的抗血清对各种白血病人骨髓组织进行免疫荧光染色.结果表明,急性白血病患者的NAg-1阳性细胞率显著高于正常人及各种非白血病贫血患者.在处于完全缓解的白血病患者中,具有较高的NAg-1阳性率者(>10％)比较低者(<10％)更易复发.
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| 关 键 词： | 核仁抗原 抗血清 间接免疫荧光染色 白血病 诊断 |
THE PRELIMINARY OBSERVATION OF NUCLEOAR ANTIGEN IN LEUKEMIA DIAGNOSE |
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| Lei Sijin Wang Yongchao. THE PRELIMINARY OBSERVATION OF NUCLEOAR ANTIGEN IN LEUKEMIA DIAGNOSE[J]. Journal of Beijing Normal University(Natural Science), 1989, 0(4) |
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| Authors: | Lei Sijin Wang Yongchao |
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| Abstract: | An antibody against nucleolar antigen(NAg-1) is obtained by immunizing rabbits with nucleoli isolated from Hala Cells. After absorption with placental nucleoli, the antiserum is used to stain a variety of human leukemic cells in bone marrow by indirect immunofluoresence technique. The results show that the percentages of NAg-1 positive cells in acute leukemic patients are significantily higher than those observed for nonleukemic individuals. Patients in remission with higher percentages of NAg-1 positive cells (>10%) are prone to relapse as compared with those with lower percentages (<10%). |
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| Keywords: | nucleolar antigen antiserum indirect immunofluoresence coloration leukemia diagnose. |
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