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Study on the action of sodium selenite on the mitochondria metabolism of<Emphasis Type="Italic">Carassius auratus</Emphasis> hybrid carps liver by microcalorimetry
Authors:Li Xi  Liu Yi  Deng Feng-jiao  Qu Song-sheng
Institution:(1) College of Chemistry and Molecular Sciences, Wuhan University, 430072 Wuhan, Hubei, China;(2) College of Life Sciences, Wuhan University, 430072 Wuhan, Hubei, China;(3) State Key Lab of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, 430070 Wuhan, Hubei, China
Abstract:By using an LKB-2277 bioactivity monitor and ampoule method, the fundamental thermogenesis curves of the metabolic process of liver mitochondria fromCarassius auratus hybrid carps and the toxic effect of Na2SeO3 on it were studied at 28°C. From the thermogenesis curves, the thermokinetic equations were established under different condition. The kinetics show that Na2SeO3 has toxic action on the metabolism process ofCarassius auratus hybrid carps liver mitochondria. Foundation item: Supported by the National Science Foundation of China (29973030, 30170010 and 5020310), Chenguang Project of Wuhan and National Postdoctor Foundation of China Biography: Li Xi (1968-), female, Associate pofessor, research direction: biothermochemistry and biomaterials.
Keywords:liver mitochondria  metabolism  Na2SeO3            toxicity  microcalorimetry
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