| 2，6-二（3-甲基-1-H-吡唑）-4-溴吡啶的合成与表征 |
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| 引用本文： | 石竹,李宏涛,李新,潘利华,刘婷婷. 2，6-二（3-甲基-1-H-吡唑）-4-溴吡啶的合成与表征[J]. 吉林工学院学报, 2008, 29(1): 14-17 |
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| 作者姓名： | 石竹 李宏涛 李新 潘利华 刘婷婷 |
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| 作者单位： | 长春工业大学生物工程学院 吉林长春130012(石竹，李宏涛，李新，刘婷婷)，中国科学院长春应用化学研究所国家电化学光谱分析研究中心 吉林长春130022(潘利华) |
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| 摘 要： | 以2，6-二溴-4-氨基吡啶为起始原料，经过亲核取代，重氮化合成了新型时间分辨荧光免疫分析双功能螯合剂中间体2，6-二（3-甲基-1-H-吡唑）-4-溴吡啶化合物。结构通过IR，MS，^1HNMR和元素分析等确证，对合成条件及反应机理进行了探讨。
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| 关 键 词： | 时间分辨荧光免疫分析 2,6-二(3-甲基-1-H-吡唑)-4-溴吡啶 |
| 文章编号： | 1674-1374（2008）01-0014-04 |
| 收稿时间： | 2007-07-13 |
| 修稿时间： | 2007-07-13 |
Synthesis and characterization of 2,6-bis(3-methyl-1-H-pyrazol-1-yl)-4-bromopyridine |
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| SHI Zhu,LI Hong-tao,LI Xin,PAN Li-hua,LIU Ting-ting. Synthesis and characterization of 2,6-bis(3-methyl-1-H-pyrazol-1-yl)-4-bromopyridine[J]. Journal of Jilin Institute of Technology, 2008, 29(1): 14-17 |
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| Authors: | SHI Zhu LI Hong-tao LI Xin PAN Li-hua LIU Ting-ting |
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| Affiliation: | SHI Zhu, LI Hong-tao, LI Xin, PAN Li-hua , LIU Ting-ting (1. School of Biological Engineering, Changchun University of Technology, Changchun 130012, China; 2. National Analytical Research Center of Electrochemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, China) |
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| Abstract: | With 2,6-dibromo-4-amino pyridine as raw material,by means of nucleophilic substitution and diazotization-sandmeyer reaction,a new time-resolved fluorescence immunoassay analysis bifunctional chelate intermediate 2,6-bis(3-methyl-pyrazol-1-yl)-4-bromopyridine is prepared.Its structure is verified with IR,~1HNMR,GC-MS and element analysis,and both the systemization conditions and reaction mechanics are studied. |
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| Keywords: | time-resolved fluorescence immunoassay analysis 2 6-his(3-methyl-pyrazol-l-yl)-4-bromopyridine |
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