聚电解质逐层自组装生物矿化材料

通过人工模拟的方法,利用阴阳离子型聚电解质溶液制得自组装膜. 将装有该自组装膜的玻璃基片放入模拟体液SBF中,选择适当的条件,可诱导羟基磷灰石在其上面的沉积. 实验结果表明:SBF溶液的pH值对羟基磷灰石在膜上的诱导结晶特性有较大的影响;当pH值为7.40时,利用自组装膜和SBF模拟体液进行生物矿化得到的晶体最为细致紧密. 诱导矿化实验表明,利用聚电解质稀溶液制成的自组装膜可以成功地进行生物矿化材料的研究.

Layer-by-layer self-assembled bio-mineralized material made by polyelectrolyte

Utilizing the manual simulation method in laboratory a self-assemble multilayer was made through anion-cation polyelectrolyte weak solution. The glass substrate equipped with the self-assemble film was put into the simulated body fluid SBF, and under proper conditions the aggradation of hydroxyl apatite was induced on the film. It is shown that the pH value of the SBF solution has much influence on crystallization of hydroxyl apatite. The most compact crystal was observed at pH 7.40 with the self-assembled film and simulated body fluid. The inducing experiments of bio-mineralization indicate that the self-assemble film made from the polyelectrolyte weak solution can be successfully used in the study of bio-mineralization materials.