Mathematical Model of Extrinsic Blood Coagulation Cascade Dynamic System |
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作者单位: | TANG Yun,WANG Hong(Department of Mathematical Sciences, Tsinghua University, Beijing 100084, China);MENG Dazhi(Department of Applied Mathematics, Beijing Polytechnic University, Beijing 100022, China)
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基金项目: | 中国科学院资助项目,北京市自然科学基金,北京市教委自然科学基金 |
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摘 要: |
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Mathematical Model of Extrinsic Blood Coagulation Cascade Dynamic System |
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Authors: | TANG Yun MENG Dazhi WANG Hong |
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Abstract: | The blood coagulation system is very important to life. This paper presents a mathematical blood coagulation model for the extrinsic pathway. This model simulates clotting factor VIII, which plays an important role in the coagulation mechanism. The mathematical model is used to study the equilibrium stability, orbit structure, attractors and global stability behavior, with conclusions in accordance with the physiological phenomena. Moreover, the results provide information about blood related illnesses, which can be used for further study of the coagulation mechanism. |
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Keywords: | blood coagulation system feedback stability attractor |
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