| 银杏内酯的药理作用 |
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| 引用本文： | 卢定强,陈钧.银杏内酯的药理作用[J].江苏大学学报(自然科学版),2001,23(2):5-9. |
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| 作者姓名： | 卢定强 陈钧 |
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| 作者单位： | 江苏理工大学生物与环境工程学院, |
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| 摘 要： | 银杏内酯为银杏叶提取物及其制剂中的主要药效成分，具有抗血小板活化因子（简称ＰＡＦ活性，文中对近几十年关于银杏内酯的药理学研究进行了综述．药理学研究表明，银杏内酯（特别银杏内酯Ｂ）是血小板活化因子强有力的拮抗剂，具有抗血小板聚集、杭血栓、防治动脉粥样硬化、抗炎症和抗过敏等作用．
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| 关 键 词： | 银杏内酯 血小板活化因子 药理学 |
| 文章编号： | 1007-1741(2001)02-0005-05 |
| 修稿时间： | 2000年6月26日 |
Pharmacological Activities of Ginkgolides |
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| LU Ding-qiang,CHEN Jun.Pharmacological Activities of Ginkgolides[J].Journal of Jiangsu University:Natural Science Edition,2001,23(2):5-9. |
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| Authors: | LU Ding-qiang CHEN Jun |
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| Abstract: | Ginkgolides are the main components with benefic clinical efficacy in Ginkgo biloba leaf extracts and Ginkgo preparations, and they are antagonists against platelet-activating factor (PAF). In this paper, pharmacological studies on ginkgolides in the past decades are reviewed. The pharmacological studies show ginkgolides, especially ginkgolide B, are potent antagonists against PAF. Therefore, they exert inhibition of platelet aggregation, prevention of thrombus, prevention of endotoxic shock, protection of myocardial ischeamia, anti-inflammation, anti-allergy and so on. |
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| Keywords: | ginkgolides platelet-activating factor pharmacology |
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