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Monoamine oxidase activity in tissues of spontaneously hypertensive rats
Authors:F. M. Lai  S. Spector
Affiliation:(1) Department of Physiological Chemistry and Pharmacology, Roche Institute of Molecular Biology, 07110 Nutley, New Jersey, USA;(2) Present address: Cardiovascular-CNS Disease Research Section Lederle Labs, Division of American Cyanamid Co. Pearl River, 10965 New York, USA
Abstract:
Summary Monoamine oxidase (MAO) activity was assayed both in central and peripheral blood vessels of spontaneously hypertensive rats (SHR) and age-matched normotensive Wistar Kyoto rats (WKR). The activity of MAO in the brain and peripheral vasculature was essentially the same in both SHR and WKR. It can therefore be concluded that central and peripheral vascular MAO activity is not altered in the genetically hypertensive animals.
Keywords:
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