Physiological state of submitochondrial particles and their susceptibility to Triton X-100 |
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Authors: | F M Goñi J M Valpuesta M C Barbero E Rial J I G Gurtubay J M Macarulla |
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Institution: | (1) Departments of Biochemistry and Biology, Faculty of Science, P.O. Box 644, Bilbao, (Spain) |
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Abstract: | Summary The solubilizing effect of Triton X-100 on beef heart submitochondrial particles (ETPH) has been studied under various physiological conditions. Coupled, uncoupled and azide-inhibited ETPH particles have been studied. Quantitative and qualitative differences are found in the proteins solubilized by the detergent from ETPH particles under the various conditions tested.Acknowledgments: This work was supported in part by a grant from a Spanish Comisión Asesora para la Investigación Cientifica y Técnica. M.C. Barbero was recipient of a scholarship from the Basque Government. |
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