Movement of microtubules by single kinesin molecules |
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Authors: | J Howard A J Hudspeth R D Vale |
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Affiliation: | Department of Physiology, University of California School of Medicine, San Francisco. |
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Abstract: | Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles along microtubules. Using a new technique for measuring the movement produced in vitro by individual kinesin molecules, it is shown that a single kinesin molecule can move a microtubule for several micrometers. New information about the mechanism of force generation by kinesin is presented. |
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