Spectrin-based skeleton as an actor in cell signaling |
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| Authors: | B.?Machnicka,R.?Grochowalska,D.?M.?Bogus?awska,A.?F.?Sikorski mailto:afsbc@ibmb.uni.wroc.pl" title=" afsbc@ibmb.uni.wroc.pl" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,M.?C.?Lecomte |
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| Affiliation: | 1.Faculty of Biological Sciences,University of Zielona Góra,Zielona Góra,Poland;2.Laboratory of Cytobiochemistry, Biotechnology Faculty,University of Wroclaw,Wroclaw,Poland;3.Inserm, UMR-S 665,Paris,France;4.Universite Paris Diderot, Paris 7,Paris,France;5.Institut National de la Transfusion Sanguine,Paris,France |
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| Abstract: | ![]()
This review focuses on the recent advances in functions of spectrins in non-erythroid cells. We discuss new data concerning the commonly known role of the spectrin-based skeleton in control of membrane organization, stability and shape, and tethering protein mosaics to the cellular motors and to all major filament systems. Particular effort has been undertaken to highlight recent advances linking spectrin to cell signaling phenomena and its participation in signal transduction pathways in many cell types. |
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