Timing of single daily meal influences relations among human circadian rhythms in urinary cyclic AMP and hemic glucagon,insulin and iron |
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| Authors: | F. Goetz J. Bishop F. Halberg R. B. Sothern R. Brunning B. Senske B. Greenberg D. Minors P. Stoney I. D. Smith G. D. Rosen D. Cressey E. Haus M. Apfelbaum |
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| Affiliation: | (1) Department of Medicine and Chronobiology Laboratories, Department of Laboratory Medicine and Pathology, University of Minnesota, 55455 Minneapolis, Minnesota, USA;(2) Department of Laboratories, St. Paul-Ramsey Hospital, 55101 St. Paul, Minnesota, USA;(3) Hospital Bichat, Paris, (France) |
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| Abstract: | ![]()
Summary Relations among circadian rhythms in serum iron, glucagon and insulin and urinary cyclic AMP excretion differ drastically when diurnally active, nocturnally resting human adults consume all daily food for one week as breakfast only and for another week as dinner only—a finding of interest to diverse fields, e.g., for optimizing certain kinds of therapy or for a better utilization of calories.Supported by grants (No. RR-400 from the General Clinical Research Centers Program of the Division of Research Resources, National Institutes of Health, USPHS and Nos. 5-K6-GM-13, 981 and 1RO1-CA-14445-01) and grant No. 20, Fondation de l'industrie pharmaceutique pour la recherche. |
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