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Serum inhibitory activity on granulocyte-macrophage colony formation
Authors:M Szmitkowski
Institution:(1) Department of Clinical Diagnostics, Institute of Biochemistry and Medical Analytics, Medical School, PL-15-276 Bialmidotystok, (Poland)
Abstract:Summary Normal and chloroform-extracted human sera, fractionated by Sephadex column chromatography, have been tested for inhibitory activity on granulocyte-macrophage (GM) colony formation. It was found that this activity is connected with lipoproteins (inhibitors of granulocyte-macrophage colony stimulating factor) and low molecular weight substances (7000; 13,000) which can act as specific polypeptide chalones.
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