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傅里叶红外光谱法在肿瘤分析中的应用
引用本文:何建川,王建华,文宗河,卫亚丽.傅里叶红外光谱法在肿瘤分析中的应用[J].重庆大学学报(自然科学版),2004,27(12):127-130.
作者姓名:何建川  王建华  文宗河  卫亚丽
作者单位:重庆大学,生物工程学院,生物力学与组织工程教育部重点实验室,重庆,400030;重庆大学,生物工程学院,生物力学与组织工程教育部重点实验室,重庆,400030;重庆大学,生物工程学院,生物力学与组织工程教育部重点实验室,重庆,400030;重庆大学,生物工程学院,生物力学与组织工程教育部重点实验室,重庆,400030
基金项目:重庆市应用基础研究基金
摘    要:综述了傅里叶红外光谱(FTIR)在鉴定癌症中的应用研究进展.目前,对其诊断主要是依靠病理学诊断,但是病理学诊断不仅过程烦琐,而且常受人为因素影响.傅里叶红外光谱及其相关技术的迅速发展,使其越来越广泛用于蛋白质,核酸等生物大分子的结构研究上,同时已开始更深入地应用于研究细胞和组织等更加复杂的体系.研究结果表明,FTIR可以从分子水平上揭示肿瘤组织的特性,极有可能发展成为一种可定量化地鉴定肿瘤的手段.

关 键 词:傅里叶变换红外光谱  肿瘤  分析  进展
文章编号:1000-582X(2004)12-0127-04
修稿时间:2004年8月10日

Application and Progress in Cancer Analysis by FTIR Spectroscopy
HE Jian-chuan,WANG Jian-hu,WEN Zong-he,WEI Ya-liMinistry of Education,College of Bioengineering,Chongqing University,Chongqing,China.Application and Progress in Cancer Analysis by FTIR Spectroscopy[J].Journal of Chongqing University(Natural Science Edition),2004,27(12):127-130.
Authors:HE Jian-chuan  WANG Jian-hu  WEN Zong-he  WEI Ya-liMinistry of Education  College of Bioengineering  Chongqing University  Chongqing  China
Institution:HE Jian-chuan,WANG Jian-hua,WEN Zong-he,WEI Ya-liMinistry of Education,College of Bioengineering,Chongqing University,Chongqing 400030,China)
Abstract:The research progress and the application of FTIR spectroscopy on diagnosing cancer are reviewed. The cancer is one of the tallest diseases of the rate of human beings. At present, its diagnosis primarily depends on the pathology one. The process of pathology diagnosis is bother and often suffers the influence of the artificial factors. Along with the rapid development of FTIR spectroscopy and its correlative technique, the FTIR spectroscopy has been applied not only to studying the structure of big biologic molecules like protein or nucleic acid, but also to studying more and more complicated system like cells and tissues. The research expresses that FTIR spectroscopy can open out the characteristics of tissues of cancer from the molecular level, and it is very possible that FTIR will be a quantitative instrument of diagnosing cancer.
Keywords:FTIR spectroscopy  cancer  analysis  progress
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