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| 金耳水溶性多糖的部分化学性质及抑瘤试验 | |
| 引用本文： | 苑小林 张培德. 金耳水溶性多糖的部分化学性质及抑瘤试验[J]. 复旦学报(自然科学版), 1996, 35(6): 703-706 |
| 作者姓名： | 苑小林 张培德 |
| 作者单位： | 复旦大学生物化学系 |
| 摘 要： | 金耳子实体经热水抽提，反复经Ｓｅｖａｇ法脱蛋白，获得金耳多糖，Ｓｅｐｈａｒｏｓｅ ４Ｂ分级分离呈现双峰（Ａ和Ｂ）。其峰Ａ的相对分子质量介于１０＾５￣１０＾６之间。峰Ａ组分经醋酸纤维薄膜电泳鉴定，呈现单一谱带，为一纯多糖。利用硅胶Ｇ薄板层析技术，确定峰Ａ组分主要由葡萄糖、甘露糖、半乳糖组成。利用人肺腺癌裸小鼠模型ＬＡＸ－８３对金耳多糖全组分进行抑瘤试验，结果表明有明显抑瘤疗效。 |
| 关 键 词： | 金耳 菌类药 多糖 化学性质 肿瘤 |
Preliminary study on chemical properties of a soluble polysaccharide from the mushnoom Tremella aurantia, and its oncosuppressive activity |
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| Yuan Xiaolin, Zhang Peide, Chen Shigen. Preliminary study on chemical properties of a soluble polysaccharide from the mushnoom Tremella aurantia, and its oncosuppressive activity[J]. Journal of Fudan University(Natural Science), 1996, 35(6): 703-706 | |
| Authors: | Yuan Xiaolin Zhang Peide Chen Shigen |
| Affiliation: | Department of Biochemistry |
| Abstract: | A soluble polysaccharide was extracted by hot-water from the mushnoom Tremella aurantia. and other proteins were removed by the Sevag procedure. The polysaccharide showed two peaks(A and B) in Sepharose 4B chromatography. peak A was of a Mr. 105-106 and its major components were glucose .galactose and manose. A marked oncosuppressive activity was demonstrated by feeding and injecting pert tonealy the polysaccharide to nude mice carrying tumor(LAX-83). |
| Keywords: | Tremella aurantia polysaccharide |
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