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Presence of hepcidin-25 in biological fluids: Bile,ascitic and pleural fluids |
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| Authors: | Jayantha Arnold Arvind Sangwaiya Vijay Manglam Frank Geoghegan Mark Thursz Mark Busbridge |
| Institution: | Department of Gastroenterology Ealing Hospital NHS Trust Uxbridge Road London UB1 3HW United Kingdom Department of Biochemistry Department of Hepatology St Mary s Hospital NHS Trust Imperial College Praed Street London W2 1NY Department of Clinical Chemistry Charing Cross and Hammersmith Hospital NHS Trust Fulham Palace Road London W6 8RF |
| Abstract: | AIM: To examine body fluids such as ascitic fluid (AF),saliva,bile and pleural effusions for the presence of hepcidin using a novel radioimmunoassay (RIA).METHODS: Serum samples were collected from 25 healthy volunteers (mean age: 36 ± 11.9 years,11 males,14 females).In addition bile was obtained from 12 patients undergoing endoscopic retrograde cholangiopancreatography (mean age: 66.9 ± 16.7 years,M:F = 5:7).Saliva was collected from 17 healthy volunteers (mean age: 35 ± 9.9 years,M:F = 8:9).Pleural and AF... |
| Keywords: | Hepcidin Hepcidin assay Hepcidin in biological fluids Hepcidin in ascitic fluid Bile Exudates Antimicrobial peptides |
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