血管张力在大鼠血栓栓塞大脑中动脉脑梗死模型中的应用

目的 利用血管张力固定改良PE管，制作血栓栓塞大脑中动脉脑梗死（Embolic middle cerebral artery occlusion, eMCAO）大鼠模型。方法 采用清洁级Sprague-Dawley大鼠20只制作eMCAO模型，均为单人制作，利用血管张力固定改良PE管。 结果 改良PE插管均成功，大鼠eMCAO造模成功率90%，制作时间每只平均30 min。 结论 利用血管张力法可单人操作制作大鼠eMCAO模型，有效节省造模所需时间以及人力物力。

The Vascular Tone in Establishing Rat Model of Embolic Middle Cerebral Artery Occlusion

Objective To improve the method of establishing embolic middle cerebral occlusion ( eMCAO ) rat model. Method Twenty Sprague-Dawley rats were used to establish the rat eMCAO model , the modified PE tube was fixed and inserted by using the vascular tone. Result The modified PE tube was all inserted, the average time of making the eMCAO model was 30 min , 90 % of the rats was successfully made of eMCAO. Conclusion The vascular tone can be used in the model making of rat eMCAO with reducing the time and labor cost.