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Meclofenamate does not reduce chronic hypoxic pulmonary vasoconstriction
Authors:S D Roos  E K Weir  J T Reeves
Institution:(1) Cardiovascular Pulmonary Research Laboratory, University of Colorado medical Center, 4200 East Ninth Avenue, 80220 Denver, Colorado, USA
Abstract:Summary There was no reduction in the pulmonary pressor response to hypoxia following inhibition of prostaglandin synthesis in rats exposed to chronic hypoxia. A fall in left ventricular weight suggested that systemic pressure may have been reduced after inhibition of prostaglandin synthesis in normoxic rats.This work was supported by NIH grant No. HL14985.
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